Michèle Kanhonou

@article{sebaaly_1707,

title = {Surgical site infection in spinal metastasis: incidence and risk factors},

author = {Amer Sebaaly and Shedid Daniel and Boubez Ghassan and Zairi Fahed and Michèle Kanhonou and Yuh Sung-Joo and Wang Zhi},

url = {https://www.thespinejournalonline.com/article/S1529-9430(18)30004-4/fulltext},

year  = {2018},

date = {2018-01-01},

journal = {Spine Journal},

volume = {18},

number = {8},

pages = {1382-1387},

abstract = {Background

Surgical site infection (SSI) in spinal metastasis surgery represents the most common postoperative surgical complication with high morbidity and mortality.

Objective

This study aims to evaluate the incidence of SSI in spinal metastasis surgery and its risk factors.

Study Design

This is a retrospective analysis of a prospectively collected data.

Methods

Preoperative, operative, and postoperative data were collected together with the modified Tokuhashi score and Frankel score at all time checkpoints. Surgical site infection was divided into superficial and deep SSI, as well as early (<90 days) and late SSI. Multiple logistic regression analysis was performed to identify independent risk factors, with p<.05 as significance threshold.

Results

A total of 297 patients were included, with an incidence of SSI of 5.1% (superficial SSI: 3.4%; deep SSI: 1.7 %). Cervicothoracic surgery was associated with the highest incidence of SSI, whereas cervical surgery had the lowest incidence. Smoking, higher number of spinal metastasis, elevated body mass index (BMI), and higher ASA (American Society of Anesthesiologist) score were the preoperative factors associated with increased risk of SSI. Increased intraoperative blood loss and increased number of fixed vertebra increased the SSI incidence. SSI increased hospital stay by a mean of 12 days. When all these variables are analyzed in a multiple regression model, only surgical time?4 hours and ASA?3 were found to be independent risk factors for the occurrence of SSI.

Conclusion

This paper represents the largest series of spinal metastasis with a mean incidence of SSI of 5.1%. Smoking, higher BMI, higher number of spinal metastasis, higher ASA score, higher number of fused vertebra, intraoperative bleeding?2000?mL, and neurologic deterioration are risk factors for SSI occurrence. Only ASA?3 and operative duration?4 hours are independent risk factors for this complication occurrence. Finally, SSI occurrence is associated with increased hospital stay, increased 30-day mortality rate, and decreased survival rates.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{zeighami_1708,

title = {Tibio-femoral Joint Contact in Healthy and Osteoarthritic Knees during Quasi-Static Squat: A Bi-planar X-Ray Analysis},

author = {Ali Zeighami and Dumas Raphael and Michèle Kanhonou and Nicola Hagemeister and Frédéric Lavoie and Jacques A. de Guise and Rachid Aissaoui},

url = {https://www.sciencedirect.com/science/article/abs/pii/S0021929017300167?via%3Dihub},

year  = {2017},

date = {2017-02-01},

journal = {Journal Of Biomechanics},

volume = {53},

number = {53},

pages = {178-184},

abstract = {The aim of this study was to quantify the tibio-femoral contact point (CP) locations in healthy and osteoarthritic (OA) subjects during a weight-bearing squat using stand-alone biplanar X-ray images. Ten healthy and 9 severe OA subjects performed quasi-static squats. Bi-planar X-ray images were recorded at 0°, 15°, 30°, 45°, and 70° of knee flexion. A reconstruction/registration process was used to create 3D models of tibia, fibula, and femur from bi-planar X-rays and to measure their positions at each posture. A weighted centroid of proximity algorithm was used to calculate the tibio-femoral CP locations. The accuracy of the reconstruction/registration process in measuring the quasi-static kinematics and the contact parameters was evaluated in a validation study. The quasi-static kinematics data revealed that in OA knees, adduction angles were greater (p<0.01), and the femur was located more medially relative to the tibia (p<0.01). Similarly, the average CP locations on the medial and lateral tibial plateaus of the OA patients were shifted (6.5±0.7?mm; p<0.01) and (9.6±3.1?mm; p<0.01) medially compared to the healthy group. From 0° to 70° flexion, CPs moved 8.1±5.3?mm and 8.9±5.3?mm posteriorly on the medial and lateral plateaus of healthy knees; while in OA joints CPs moved 10.1±8.4?mm and 3.6±2.8?mm posteriorly. The average minimum tibio-femoral bone-to-bone distances of the OA joints were lower in both compartments (p<0.01). The CPs in the OA joints were located more medially and displayed a higher ratio of medial to lateral posterior translations compared to healthy joints.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{kanhonou_1709,

title = {A method to evaluate the 3D pseudo-kinematic of the osteoarthritic knee},

author = {Michèle Kanhonou and Thierry Cresson and Julien Clément and Frédéric Lavoie and Nicola Hagemeister and Jacques A. de Guise},

url = {https://www.oarsijournal.com/article/S1063-4584(15)00960-7/fulltext},

year  = {2015},

date = {2015-04-01},

journal = {Osteoarthritis And Cartilage},

volume = {23},

number = {Suppl2},

pages = {A117-A118},

abstract = {Purpose: Knee osteoarthritis (OA) is diagnosed and graded with a radiographic evaluation of the joint. However, there is no clear corre- lation between this grade and patient functional outcome scores (Sanghi et al. 2011; Zifchock et al. 2011, Alkan et al. 2013). This leads to the need of a quantitative and precise measure to represent the knee function. In the recent years, to evaluate healthy and OA knee function, the trend was to track skin markers displacements, known to be affected by soft tissue artefacts (Leardini et al., 2005). On the other hand, with imagery-based methods, 3D model acquired either from CT scan or Magnetic resonance imaging are matched on 2D fluoroscopic images (kinematics) or several radiographs (pseudo-kinematics) (Moro-Oka et al., 2006). With objects of known geometry in the radiographic scene (bone-embedded tantalum beads or prostheses), this matching allows attaining kinematic measurement accuracy <1 and <1mm. Without tantalum beads or prostheses, the process lacks reliability and accuracy. Thus, our goal is to present an intrinsic computation method - without any object added in the scene - and to validate its reliability on patients' images as well as its accuracy on simulated radiographs in a pseudo- kinematic context.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{kanhonou_1710,

title = {A method to study 3D knee pseudo-kinematics using low-dose stereo-radiography during static squat},

author = {Michèle Kanhonou and Thierry Cresson and Julien Clément and Frédéric Lavoie and Nicola Hagemeister and Jacques A. de Guise},

url = {https://www.tandfonline.com/doi/abs/10.1080/10255842.2014.931549},

year  = {2014},

date = {2014-08-01},

journal = {Computer Methods In Biomechanics And Biomedical Engineering},

volume = {17},

number = {1},

pages = {138-139},

abstract = {To investigate clinical questions as kinematic or postural differences between healthy and pathological populations,the current trend is to couple imagery to movement or to posture. To do so, researchers generally register a three-dimensional (3D) model acquired from either CT scan or magnetic resonance imaging on 2D fluoroscopic images(registration on dynamic activities) or several radiographs (registration on posture or pseudo-kinematics) (Moro-oka et al.2007). The literature suggests the use of so-called?extrinsic 2D/3D registration'. This implies the need of geometrical objects in the radiographic scene. Embedded tantalum beads or prostheses (Scarvell et al.2010; Sharmaet al.2012), well detectable on the radiographs, are generally used. They allow attaining the expected measurement accuracy <1° and <1mm. When no tantalum beads or prostheses are present, the registration process lacks reliability and accuracy because of the difficulty to extract precise information from the radiographic images (blurry contours, superimposition of structures and cylindrical nature of long bones) (Belvedere et al.2013). The goal of this work was to present an intrinsic 2D/3D registration method and to validate its reliability on patients' images as well as its accuracy on simulated radiographs in a pseudo-kinematic context.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}

@article{kanhonou_1711,

title = {2D/3D Registration of Personalized Knee 3D Models on Biplane Radiographs for Morpho-Functional Study},

author = {Michèle Kanhonou and Thierry Cresson and Julien Clément and Frédéric Lavoie and Nicola Hagemeister and Jacques A. de Guise},

url = {https://link.springer.com/article/10.1007%2Fs11548-014-1017-9},

year  = {2014},

date = {2014-06-01},

journal = {International Journal Of Computer Assisted Radiology And Surgery},

volume = {9},

pages = {31-34},

abstract = {To investigate kinematic or postural differences between healthy and pathological  population,  researchers  generally  register  a  3D  model acquired either from CT scan or MRI on 2D fluoroscopic images or several  radiographs  (registration  on  static  posture  images:  pseudo-kinematics). To attain the needed measurement  accuracy, the literature  suggests  the  use  of  extrinsic  2D/3D  registration,  with  known geometries in the scene (embedded tantalum beads or prostheses [1]). The goal of this work is to present an intrinsic 2D/3D registration method, to validate its reliability on patients' images and its accuracy on simulated radiographs in a pseudo-kinematic context.},

keywords = {},

pubstate = {published},

tppubtype = {article}

}